GPCRdb

APLYSAMINE

Agent/drug
Bioactivity

APLYSAMINE

SMILES	CN(C)CCCOc1c(Br)cc(CCN(C)C)cc1Br
InChIKey	LWENJEAGCYZOBC-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	0
Rotatable bonds	8
Molecular weight (Da)	406.0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Rat	Histamine	A	pKi	6.60	6.60	6.60	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	7.52	7.52	7.52	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Guinea pig	Histamine	A	pIC50	6.30	6.30	6.30	ChEMBL

Showing 1 to 1 of 1 entry

APLYSAMINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.