CHEMBL383167


SMILES Cc1cc(C)c2cccc(OCc3c(Cl)ccc(S(=O)(=O)NC(C)(C)C(=O)N4CCN(C(=O)[C@@H](N)CCCCN(C)C)CC4)c3Cl)c2n1
InChIKey JGUBUKWSOPEYMS-MHZLTWQESA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 720.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B2 BKRB2 Guinea pig Bradykinin A pKd 9.7 9.7 9.7 ChEMBL
B2 BKRB2 Human Bradykinin A pKi 9.2 9.2 9.2 ChEMBL
B2 BKRB2 Human Bradykinin A pKd 8.5 8.5 8.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database