CHEMBL385310


SMILES CC(Oc1ccccc1-c1ccsc1)C1=NCCN1
InChIKey IAIZHDGEGFGNMO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 272.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.88 6.88 6.88 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.34 7.34 7.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 7.03 7.03 7.03 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.12 7.12 7.12 ChEMBL