BOLDINE


SMILES COc1cc2c(cc1O)C[C@H]1c3c(cc(O)c(OC)c3-2)CCN1C
InChIKey LZJRNLRASBVRRX-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 327.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.54 6.54 6.54 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKi 6.5 6.5 6.5 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 8.31 8.31 8.31 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.43 6.43 6.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 6.4 6.4 6.4 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 6.28 6.29 6.3 ChEMBL