CHEMBL1086626


SMILES Cc1[nH]c(-c2ccccc2)cc1C(=O)NCCCN1CCN(c2cccc(Cl)c2Cl)CC1
InChIKey OHODDACZFUFQDV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.34 6.34 6.34 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.73 5.73 5.73 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.85 5.85 5.85 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.22 6.22 6.22 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.48 6.48 6.48 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.52 6.52 6.52 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.97 5.97 5.97 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.93 6.93 6.93 ChEMBL