CHEMBL1086754


SMILES Cc1c(C(=O)NCCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc(-c2ccccc2)n1C
InChIKey YIHQDWZWZRGAIH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 6.01 6.01 6.01 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 6.15 6.15 6.15 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.92 7.92 7.92 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.04 6.04 6.04 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.33 7.33 7.34 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.59 5.59 5.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 7.27 7.27 7.27 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.48 6.48 6.48 ChEMBL