GPCRdb

CHEMBL389665

Agent/drug
Bioactivity

CHEMBL389665

SMILES	Cc1ccccc1C(c1ccccc1C)N1CCC(O)(c2ccccc2)CC1
InChIKey	MHYKPRJMOSXVFG-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	371.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	5.24	5.24	5.24	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	5.77	5.77	5.77	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	5.67	5.67	5.67	ChEMBL
NOP	OPRX	Human	Opioid	A	pKi	8.40	8.40	8.40	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NOP	OPRX	Human	Opioid	A	pEC50	6.94	6.94	6.94	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL389665

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.