CHEMBL390253


SMILES O=C(NCC(O)CCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(-c2ccccn2)cc1
InChIKey ZQBFPGSJRSEUAX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 498.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.81 7.81 7.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.3 9.3 9.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.55 7.55 7.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.47 8.47 8.47 ChEMBL
D3 DRD3 Human Dopamine A pIC50 8.27 8.27 8.27 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.05 7.05 7.05 ChEMBL