CHEMBL375302


SMILES CC[C@@H]1NCCN2C(=O)c3c(cccc3C(F)(F)F)[C@H]12
InChIKey IAQXADIYISFYCJ-CMPLNLGQSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 284.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.53 6.53 6.53 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 6.32 6.32 6.32 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.9 6.9 6.9 ChEMBL