CHEMBL3765778


SMILES Cc1ccc(C(C)(C)O)cc1-c1ccc2c(n1)n(C)c(=O)n2CC(C)(C)C
InChIKey QLTCKDVHRJIRHT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 367.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 5.7 5.7 5.7 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 6.67 7.13 7.6 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.22 6.88 7.21 ChEMBL