CHEMBL376676


SMILES C[C@H]1CNC[C@H]2c3cccc(C(F)(F)F)c3C(=O)N12
InChIKey MNIPSARJNABKIZ-XVKPBYJWSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 270.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.94 6.94 6.94 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.0 7.0 7.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.09 7.09 7.09 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.43 6.43 6.43 ChEMBL