CHEMBL3771331


SMILES CCNC(=O)c1cccc(NC2=NC(N)=NC3(CCCCC3)N2)c1
InChIKey MWRXFEODZOVBTP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 3
Molecular weight (Da) 328.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.56 7.56 7.56 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.17 5.17 5.17 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.23 5.23 5.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 6.98 6.98 6.98 ChEMBL