CHEMBL377961


SMILES CCN(CC)CC(c1ccccc1F)N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2)CC1
InChIKey PUBNSQFRKLLQSF-NWBPNMJXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 619.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.24 5.24 5.24 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.02 6.02 6.02 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.16 5.16 5.16 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.39 7.54 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database