CHEMBL391902


SMILES Cc1ccc(N2CCN(C(=O)[C@@H]3CN(C4CCOCC4)C[C@H]3c3ccc(Cl)cc3)CC2)c([C@@H](N)C(C)C)c1
InChIKey KHUSEOUYELGLMC-LXQNXJGFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 538.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.47 5.47 5.47 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.62 6.62 6.62 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.8 5.8 5.8 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.92 7.94 7.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 7.62 7.62 7.62 ChEMBL