CHEMBL378772


SMILES O=C(NCC1CCN(CC2CC2)CC1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1
InChIKey UUQTXJMGYQWWJC-RQOYOAKWSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 716.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.8 5.8 5.8 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.7 7.7 7.7 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.77 9.77 9.77 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.14 7.14 7.14 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.19 7.19 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database