CHEMBL392573


SMILES Cc1cc2ncc(-c3ccc4cc(CCN5CCC[C@H]5C)ccc4n3)c(C)n2n1
InChIKey NJPWXCCVGLUPFM-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 385.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 9.03 9.03 9.04 ChEMBL
H3 HRH3 Human Histamine A pKi 9.62 9.62 9.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pEC50 8.3 8.3 8.3 ChEMBL
H3 HRH3 Human Histamine A pEC50 8.95 8.95 8.95 ChEMBL