CHEMBL381357


SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1
InChIKey MCHDZFRIUNRJGL-GZXHTMMISA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 7
Rotatable bonds 15
Molecular weight (Da) 690.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.64 5.64 5.64 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.79 5.79 5.79 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 8.0 8.0 8.0 ChEMBL