CHEMBL3818047


SMILES O=C(CCCN1CCc2ccccc2C1)c1ccc(Cl)cc1
InChIKey HKUPNFQZELWUIO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 313.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.07 7.58 8.09 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.53 5.53 5.53 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.44 8.45 8.45 ChEMBL
H1 HRH1 Human Histamine A pKi 6.22 6.22 6.22 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.77 7.77 7.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.09 8.09 8.09 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database