CHEMBL3819427


SMILES NC(=O)c1ccc(C(=O)CCCN2CCc3ccccc3C2)cc1
InChIKey HNPAUMYBQXZAJH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.69 6.69 6.69 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.72 5.72 5.72 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.91 7.92 7.92 ChEMBL
H1 HRH1 Human Histamine A pKi 5.8 5.82 5.85 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.75 7.82 7.89 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.66 6.66 6.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database