CHEMBL3935692


SMILES Cc1ncoc1-c1nnc(SCCCN2CC[C@]3(C[C@@H]3c3ccc(C(F)(F)F)cc3)C2)n1C
InChIKey MNAFRWGRFIBAQX-GCJKJVERSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 477.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.56 6.56 6.56 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.51 6.51 6.51 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.78 9.04 9.2 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.53 6.78 7.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database