CHEMBL393584


SMILES Cc1ccc([C@@H](CC(C)C)NC(=O)CCN(C)C)c(N2CCN(C(=O)[C@H](C)Cc3ccc(Cl)cc3Cl)CC2)n1
InChIKey GLNBATBKCBLDAT-JIPXPUAJSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 575.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.19 5.19 5.19 ChEMBL
MC5 MC5R Human Melanocortin A pKi 5.92 5.92 5.92 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.48 5.48 5.48 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.6 8.6 8.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 7.31 7.31 7.31 ChEMBL