GPCRdb

CHEMBL393581

Agent/drug
Bioactivity

CHEMBL393581

SMILES	Cc1c(-c2ccc3cc(CCN4CCC[C@H]4C)ccc3n2)cnn1-c1ccccn1
InChIKey	TVAWFBREUZKKRV-GOSISDBHSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	397.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Rat	Histamine	A	pKi	8.15	8.82	9.04	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	9.59	9.59	9.59	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Rat	Histamine	A	pEC50	8.44	8.44	8.44	ChEMBL
H₃	HRH3	Human	Histamine	A	pEC50	8.85	8.85	8.85	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL393581

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.