GPCRdb

CHEMBL393584

Agent/drug
Bioactivity

CHEMBL393584

SMILES	Cc1ccc([C@@H](CC(C)C)NC(=O)CCN(C)C)c(N2CCN(C(=O)[C@H](C)Cc3ccc(Cl)cc3Cl)CC2)n1
InChIKey	GLNBATBKCBLDAT-JIPXPUAJSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	11
Molecular weight (Da)	575.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pKi	5.19	5.19	5.19	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pKi	5.48	5.48	5.48	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	8.60	8.60	8.60	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pKi	5.92	5.92	5.92	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₄	MC4R	Human	Melanocortin	A	pIC50	7.31	7.31	7.31	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL393584

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.