CHEMBL385126


SMILES CC(=O)c1cc(F)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3
InChIKey YYAWOSLKARYYMV-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 399.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
IP PI2R Human Prostanoid A pKi 4.85 4.85 4.85 ChEMBL
DP1 PD2R Human Prostanoid A pKi 8.96 8.96 8.96 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 6.51 6.51 6.51 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 5.92 5.92 5.92 ChEMBL
TP TA2R Human Prostanoid A pKi 7.85 7.85 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pIC50 7.82 8.68 9.54 ChEMBL
TP TA2R Human Prostanoid A pIC50 5.85 5.85 5.85 ChEMBL