CHEMBL394218


SMILES COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(C(=O)NC4CN5CCC4CC5)cc13)CC2
InChIKey RKQFKAILJGXGRP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 505.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.07 6.07 6.07 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 9.1 9.1 9.1 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.38 7.38 7.38 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.38 7.38 7.38 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 6.07 6.07 6.07 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 9.1 9.1 9.1 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database