CHEMBL3884161


SMILES O=c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)nn1-c1cc(Cl)ccc1Cl
InChIKey JRNSVVDDKAJZGF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 516.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 6.73 6.73 6.73 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.57 8.57 8.57 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 11.0 11.0 11.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.93 7.93 7.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database