CHEMBL3885471


SMILES O=c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)nn1-c1cccc(Cl)c1Cl
InChIKey MJNIHQSWWWZHAP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 516.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 7.78 7.78 7.78 ChEMBL
D2 DRD2 Rat Dopamine A pKi 9.7 9.7 9.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.95 6.95 6.95 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.03 8.03 8.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database