CHEMBL3981554


SMILES O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(F)c2F)cc1
InChIKey ZHIYYJVFRSDGIT-SATSMNEMSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.5 5.71 5.91 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.23 7.46 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 6.79 7.45 8.1 ChEMBL
EP3 PE2R3 Human Prostanoid A pEC50 5.0 5.0 5.0 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 7.52 8.61 9.7 ChEMBL