GPCRdb

CHEMBL397770

Agent/drug
Bioactivity

CHEMBL397770

SMILES	OC1(c2cccc(Cl)c2Cl)CCN(Cc2c[nH]c3ccccc23)CC1
InChIKey	ASKCQUQTSBOXCM-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	374.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	7.58	7.58	7.58	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	6.56	6.56	6.56	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	5.81	5.81	5.81	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	7.46	7.46	7.46	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	6.63	6.63	6.63	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL397770

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.