GPCRdb

CHEMBL398368

Agent/drug
Bioactivity

CHEMBL398368

SMILES	CCCCCCOc1ccc(C2(O)CCN(Cc3c[nH]c4ccccc34)CC2)cc1
InChIKey	FISUUARMPJZKMS-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	9
Molecular weight (Da)	406.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pKi	6.80	6.80	6.80	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	5.71	5.71	5.71	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	5.83	5.83	5.83	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	6.67	6.67	6.67	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL398368

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.