CHEMBL3946661


SMILES c1ccc(OC[C@@H]2CN(CCN3CCc4ccccc43)CCO2)cc1
InChIKey ZKTUDHGKQCWRDH-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 338.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Mouse Adrenoceptors A pKi 5.57 5.57 5.57 ChEMBL
α1B ADA1B Mouse Adrenoceptors A pKi 5.14 5.14 5.14 ChEMBL
D3 DRD3 Mouse Dopamine A pKi 5.55 5.55 5.55 ChEMBL
α1D ADA1D Mouse Adrenoceptors A pKi 5.64 5.64 5.64 ChEMBL
5-HT2C 5HT2C Mouse 5-Hydroxytryptamine A pKi 5.17 5.17 5.17 ChEMBL
D4 DRD4 Mouse Dopamine A pKi 6.88 6.88 6.88 ChEMBL
5-HT2B 5HT2B Mouse 5-Hydroxytryptamine A pKi 5.84 5.84 5.84 ChEMBL
5-HT1D 5HT1D Mouse 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
D1 DRD1 Mouse Dopamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pKi 9.22 9.22 9.22 ChEMBL
D2 DRD2 Mouse Dopamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT2A 5HT2A Mouse 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
5-HT7 5HT7R Mouse 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database