CHEMBL4076673


SMILES COCCCN1CCC23c4cc(O)ccc4CC1C21CCC2C3[C@@H](CN2C(=O)c2ccccc2)O1
InChIKey JQLFZIGRGRAYPG-BTNQZZBKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 474.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 8.4 8.4 8.4 ChEMBL
δ OPRD Mouse Opioid A pKi 9.43 9.43 9.43 ChEMBL
κ OPRK Guinea pig Opioid A pKi 7.69 7.69 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 7.66 7.66 7.66 ChEMBL
δ OPRD Human Opioid A pEC50 8.85 8.85 8.85 ChEMBL