GPCRdb

CHEMBL4078647

Agent/drug
Bioactivity

CHEMBL4078647

SMILES	O=c1cc(OCc2cccc(Cl)c2)nc2ccc(Oc3cccnc3)cn12
InChIKey	NRJNVAHQQJOPPW-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	379.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₅	GRM5	Human	Metabotropic glutamate	C	pKi	8.40	8.40	8.40	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₅	GRM5	Rat	Metabotropic glutamate	C	pIC50	7.85	7.85	7.85	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL4078647

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.