CHEMBL409662


SMILES CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2cc(F)ccc21
InChIKey QFHWIGIQQPTXBG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 429.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 7.15 7.15 7.15 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.47 5.47 5.47 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.79 5.79 5.79 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.73 6.73 6.73 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.79 5.79 5.79 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.71 7.71 7.71 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.02 6.02 6.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database