CHEMBL3974652


SMILES O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(F)c2)cc1
InChIKey FVIFTCKGAKHIMG-FSKZSRKQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 396.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.47 5.61 5.75 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 7.4 8.05 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.11 7.55 8.0 ChEMBL
EP3 PE2R3 Human Prostanoid A pEC50 5.43 5.43 5.43 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 9.0 9.7 10.4 ChEMBL
TP TA2R Human Prostanoid A pEC50 5.14 5.14 5.14 ChEMBL