CHEMBL3976710


SMILES O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2ccc(F)c(F)c2)cc1
InChIKey PGDLVWMBYBRVFO-QVVBJLIYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.03 5.43 5.82 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.53 7.53 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 7.52 7.52 7.52 ChEMBL
EP3 PE2R3 Human Prostanoid A pEC50 5.82 5.82 5.82 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 7.68 8.6 9.52 ChEMBL
TP TA2R Human Prostanoid A pEC50 5.61 5.61 5.61 ChEMBL