CHEMBL3985877


SMILES Cc1ncoc1-c1nnc(SCCCN2CC[C@]3(C[C@H]3c3ccc(F)cc3C(F)(F)F)C2)n1C
InChIKey LRMWMKQIJLOEPF-AVRDEDQJSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 495.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.68 5.68 5.68 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.25 6.25 6.25 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.98 8.98 8.98 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database