CHEMBL4128460


SMILES COc1cc2nc(N3CCN(C(=O)C(C)(C)C)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC
InChIKey HEMORBXXFYODCC-DLBZAZTESA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 427.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 8.18 8.18 8.18 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 9.11 9.11 9.11 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.21 8.21 8.21 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKd 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database