CHEMBL398665


SMILES N=C(N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H]2CCCN2C(=O)c2ccccc2C(=O)CCCNCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O
InChIKey YUUZCRILYWDWPO-PURVKFDZSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 10
Rotatable bonds 9
Molecular weight (Da) 953.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Human Melanocortin A pKd 9.8 9.8 9.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pIC50 7.57 7.57 7.57 ChEMBL
MC5 MC5R Human Melanocortin A pEC50 7.64 7.64 7.64 ChEMBL
MC3 MC3R Human Melanocortin A pIC50 7.96 7.96 7.96 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 6.48 6.48 6.48 ChEMBL