CHEMBL399495


SMILES C[C@@H](NC(=O)Nc1cccc(-c2nnnn2C)c1)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1
InChIKey JTVSGNGYUGCQJP-FHJLPGHOSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Crab-eating macaque Chemokine A pIC50 9.82 9.82 9.82 ChEMBL
CCR3 CCR3 Mouse Chemokine A pIC50 7.51 7.51 7.51 ChEMBL
CCR3 CCR3 Human Chemokine A pIC50 9.06 9.69 10.42 ChEMBL