CHEMBL39959


SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(CCC)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc32)cc1
InChIKey MLGCITBDCGSKQS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 562.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Human Angiotensin A pKi 8.82 8.82 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Rat Angiotensin A pIC50 8.42 8.42 8.42 ChEMBL
AT2 AGTR2 Human Angiotensin A pIC50 8.21 8.34 8.38 ChEMBL
AT1 AGTR1 Human Angiotensin A pIC50 8.82 8.82 8.82 ChEMBL
AT1 AGTR1 Rabbit Angiotensin A pIC50 8.68 8.68 8.68 ChEMBL