CHEMBL405174


SMILES CC(=O)Nc1cc2ccccc2cc1C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChIKey HQOYMPPRYNULSG-FZCBKRAZSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 8
Rotatable bonds 16
Molecular weight (Da) 717.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Mouse Melanocortin A pKd 5.6 5.6 5.6 ChEMBL
MC3 MC3R Mouse Melanocortin A pKi 5.6 5.6 5.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 7.34 7.34 7.34 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 5.1 5.1 5.1 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 7.68 7.68 7.68 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.22 7.94 8.66 ChEMBL