CHEMBL4061162


SMILES COc1ccc(C(=O)N[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@H]23)cc1
InChIKey JLZOXIUHWYFQIX-VZAVHYRXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 334.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 8.34 8.34 8.34 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 6.73 6.73 6.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 8.61 8.61 8.61 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.8 7.8 7.8 ChEMBL