CHEMBL419448


SMILES CS(=O)(=O)c1c(F)cccc1NCC1=NCCN1
InChIKey FFVMPJRYEFKURT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 271.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.64 5.64 5.64 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.59 6.59 6.59 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.26 6.26 6.26 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 5.46 5.46 5.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 6.3 6.3 6.3 ChEMBL
α1A ADA1A Human Adrenoceptors A pEC50 7.62 7.62 7.62 ChEMBL