CHEMBL4071451


SMILES O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1)c1ccc2ccccc2c1
InChIKey MJKPZFAVGMHXNU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.44 7.44 7.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.85 7.85 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database