CHEMBL4080399


SMILES O=S(=O)(NCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(O)c1
InChIKey LPJJPPHJSYTROB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 445.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.4 8.4 8.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.59 8.59 8.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database