CHEMBL4084492


SMILES O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1ccc2ccccc2c1
InChIKey BXCDGOZRLHWEFT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 465.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database