CHEMBL1242445


SMILES COc1ccccc1N1CCN(C[C@@H]2CO[C@](CN3CCCC3=O)(c3ccccc3)O2)CC1
InChIKey AOZOBKDTJZCKJE-GJZUVCINSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.15 7.15 7.15 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.9 7.9 7.9 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.28 8.28 8.28 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.95 7.95 7.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database