GPCRdb

flesinoxan

Agent/drug
Bioactivity

flesinoxan

SMILES	O=C(NCCN1CCN(c2cccc3c2OC[C@H](CO)O3)CC1)c1ccc(F)cc1
InChIKey	NYSDRDDQELAVKP-SFHVURJKSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	2
Rotatable bonds	6
Molecular weight (Da)	415.2

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	9.30	9.30	9.30	Guide to Pharmacology
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	8.77	8.77	8.77	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	6.85	6.85	6.85	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	8.18	8.18	8.18	ChEMBL

Showing 1 to 1 of 1 entry

flesinoxan

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.