GPCRdb

CHEMBL423181

Agent/drug
Bioactivity

CHEMBL423181

SMILES	COc1ccc2c(c1)CC(CCN1CCN(c3ccccn3)CC1)CC2
InChIKey	MQYILSGYILZXMS-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	5
Molecular weight (Da)	351.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	9.80	9.80	9.80	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	9.80	9.80	9.80	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	5.76	5.76	5.76	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	7.68	8.06	8.45	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL423181

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.